ea0032p991 | Thyroid (non-cancer) | ECE2013
Saba Alessandro
, Colligiani Daria
, Nannipieri Monica
, Kusmic Claudia
, Dos Remedios Cristobal
, Simonides Warner
, Iervasi Giorgio
, Zucchi Riccardo
Thyroid hormone (T3) is mostly produced in peripheral tissues by thyroxine (T4) deiodination, and its functional effects are directly related to tissue concentration, which is quite difficult to assay by conventional immunological methods. We report a novel technique, based on tandem mass spectrometry (MS/MS) coupled to HPLC, which was used in left ventricular myocardium obtained from rat and human hearts.Samples were homogenized in...